To support various message exchange patterns like one way Event Message and Request Reply messages Camel uses an Exchange interface which has a pattern property which can be set to InOnly for an Event Message which has a single inbound Message, or InOut for a Request Reply where there is an inbound and outbound message.
Here is a basic example of sending a Message to a route in InOnly and InOut modes
Route Using the Fluent Builders
Route Using the Spring XML Extensions
If you would like to use this EIP Pattern then please read the Getting Started, you may also find the Architecture useful particularly the description of Endpoint and URIs. Then you could try out some of the Examples first before trying this pattern out.